Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

443
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
443
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

52
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
52
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

6.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
6.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adaptive deep brain stimulation in Parkinson disease: clinical implementation and outlook.

Nature reviews. Neurology·2026
Same author

Who Falls After a Stroke? Evidence From a Prospective Stroke Cohort.

European journal of neurology·2026
Same author

Authors' Comments on "Adaptive Deep Brain Stimulation for Parkinson's Disease: Navigating the Roadblocks to Clinical Implementation".

Movement disorders : official journal of the Movement Disorder Society·2026
Same author

DBSsync: combining intracranial and multimodal data to investigate new biomarkers in Parkinson's disease.

NPJ Parkinson's disease·2026
Same author

Action and rest tremor map to distinct networks within the primary motor cortex.

Cell reports·2026
Same author

Transcranial ultrasound stimulation of motor networks in Parkinson's disease informed by local field potential dynamics.

Science translational medicine·2026

Related Experiment Video

Updated: Sep 11, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K

Toward a standard preoperative MRI protocol for functional neurosurgery.

Christopher Güttler1,2, Johannes Achtzehn2, Patric Blomstedt3

  • 1Institute of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.

Imaging Neuroscience (Cambridge, Mass.)
|August 13, 2025
PubMed
Summary

Standardizing MRI protocols for Deep Brain Stimulation (DBS) surgery improves electrode targeting. This study evaluated sequences, suggesting a protocol to enhance accuracy for movement disorder treatments.

Keywords:
Parkinson’s diseasedeep brain stimulationdystoniaessential tremormagnetic resonance imagingprotocol harmonizationtargeting

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.7K
Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

1.6K

Related Experiment Videos

Last Updated: Sep 11, 2025

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.8K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.7K
Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

1.6K

Area of Science:

  • Neurosurgery
  • Medical Imaging
  • Neurology

Background:

  • Deep Brain Stimulation (DBS) is crucial for movement disorders, but requires precise electrode placement.
  • Current preoperative MRI protocols for DBS vary significantly, hindering data comparison and research.
  • Accurate targeting relies on high signal-to-noise ratio in preoperative MRI scans.

Purpose of the Study:

  • To evaluate various MRI sequences for their suitability in DBS targeting.
  • To suggest a standardized MRI protocol for preoperative DBS procedures.
  • To improve the accuracy and consistency of DBS electrode placement.

Main Methods:

  • Two healthy subjects underwent scanning with multiple MRI sequences (T2w, PDw, T2FLAIRw, T2*w, SWI, FGATIR, T1TIR, QSM).
  • Twelve experienced DBS surgeons rated sequence suitability for targeting the subthalamic nucleus (STN), globus pallidus internus (GPi), and ventrointermediate (VIM) thalamus.
  • Contrast-to-noise ratios (CNR) were calculated and correlated with targeting accuracy.

Main Results:

  • T2w, SWI, QSM, and T2FLAIRw sequences were highly rated for STN-DBS targeting.
  • FGATIR, PDw, and SWI were preferred for GPi-DBS, while FGATIR was best for VIM-DBS.
  • Higher CNR correlated with improved targeting accuracy (R²=0.29 for z-scores, R²=0.18 for coordinates).

Conclusions:

  • A suggested MRI protocol can standardize preoperative imaging for DBS.
  • Optimizing MRI sequences enhances the precision of electrode placement in DBS surgery.
  • Openly sharing imaging data and protocols facilitates research and clinical practice standardization.