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After the bite: cellular responses to mosquito blood feeding
1Interdepartmental Program in Genetics and Genomics, Iowa State University, Ames, IA, USA; Department of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, IA, USA.
Trends in Parasitology
|August 13, 2025
Abstract
None:
Vial et al. performed single-cell transcriptomics and metabolomics of Aedes aegypti midgut and fat body tissues after blood feeding, characterizing novel cell types and markers, transcriptomic and metabolic responses to feeding, and insect-specific virus infection dynamics. This analysis reveals an intricate cellular ecosystem driving digestion, metabolism, reproduction, and immunity.

