Related Experiment Video
Updated: Sep 11, 2025
04:36
Author Spotlight: A Simple and Cost-Effective Method for Leukocyte Analysis in Semen
Published on: January 19, 2024
4.5K
Association of Lycopene and Male Reproductive Health: Systematic Review and Meta-Analysis.
1IVB Wellness Lab, C/Colón 12, 46004 Valencia, Spain.
International Journal of Molecular Sciences
|August 14, 2025
Summary
Lycopene supplementation may improve sperm concentration and nonprogressive motility in men, according to a systematic review. Further research is needed to confirm these modest benefits for male fertility.
Area of Science:
- Reproductive biology and nutrition.
- Antioxidant and anti-inflammatory mechanisms in male reproductive health.
Background:
- Lycopene, a carotenoid from tomatoes and watermelon, is explored for male fertility enhancement.
- Existing evidence on lycopene's efficacy for male fertility is inconsistent.
Purpose of the Study:
- To systematically review and meta-analyze the effects of lycopene supplementation on male fertility outcomes.
- To assess the current evidence regarding lycopene's impact on sperm parameters and reproductive health.
Main Methods:
- Systematic review and meta-analysis of clinical studies published until February 2025.
- Searched PubMed, Scopus, Web of Science, and Medline databases.
- Included four studies with 151 participants; calculated standardized mean differences (SMDs).
Main Results:
- Lycopene supplementation significantly improved sperm concentration (SMD 0.33) and nonprogressive motility (SMD 0.45).
- No significant effects were found on total motility, progressive motility, morphology, semen volume, or DNA damage.
- Sensitivity analyses indicated robust findings, though publication bias and heterogeneity were noted.
Conclusions:
- Lycopene supplementation may offer modest benefits for sperm concentration and nonprogressive motility in men.
- Evidence for other male fertility outcomes remains inconclusive.
- Larger, high-quality randomized trials are necessary to validate these findings and clarify lycopene's role.
More Related Videos
05:56Demonstrating a Linear Relationship Between Vascular Endothelial Growth Factor and Luteinizing Hormone in Kidney Cortex Extracts
Published on: January 22, 2020
4.9K
07:25A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
13.2K
Related Concept Videos
01:23Infertility in Males
332
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
332
01:20Disorders of the Male Reproductive System
577
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
577
01:31Overview of the Reproductive System
2.1K
The reproductive system generates offspring, ensuring the survival of the species. In humans, the reproductive system is complex and involves a variety of organs and hormones that work together to ensure successful reproduction.
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
The gonads, or primary reproductive organs, produce gametes and sex hormones. In males, the testes produce spermatozoa and testosterone, which is responsible for developing secondary male sex characteristics, including a deeper voice, larger muscles, facial and body...
2.1K
01:26Testosterone: Functions and Regulation
1.0K
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
1.0K
02:19The Y Chromosome Determines Maleness
6.9K
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
6.9K
01:25Accessory Ducts of the Male Reproductive System
1.7K
The male reproductive system is a complex network of organs and tissues that work together to produce and transport sperm. The epididymis, vasa deferens, ejaculatory ducts, and urethra are the accessory ducts involved in sperm maturation and transportation. These ducts play a critical role in the production and transportation of sperm from the testes to the urethra, where it is then released during ejaculation.
The epididymis is a small, comma-shaped organ located at the back of each testicle....
The epididymis is a small, comma-shaped organ located at the back of each testicle....
1.7K