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Updated: Sep 11, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Straightforward Access to the Dispirocyclic Framework via Regioselective Intramolecular Michael Addition

Weilun Cao1, Junmin Dong1, Xuan Pan1

  • 1State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China.

Molecules (Basel, Switzerland)
|August 14, 2025
PubMed
Abstract

Keywords:
regioselectivityspiro compoundstransition-metal free

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