Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions01:15

Impact of Pharmacokinetic–Pharmacodynamic Models: Regulatory Decisions

97
PK–PD modeling has significantly influenced FDA regulatory decisions, particularly drug approval, dosage optimization, and labeling. These models integrate pharmacokinetics (PK) and pharmacodynamics (PD) to predict drug behavior and effects, aiding in optimizing dosing regimens and enhancing the probability of clinical trial success.One notable example is Nesiritide (Natrecor®), a recombinant human brain natriuretic peptide for treating acute decompensated congestive heart failure...
97

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ecological Synthesis of Precious Metal Nanoparticles: Harnessing the Potential of Marine Algae Biomass.

Nanomaterials (Basel, Switzerland)·2025
Same author

Lignin as a Bioactive Additive in Chlorzoxazone-Loaded Pharmaceutical Tablets.

Molecules (Basel, Switzerland)·2025
Same author

New Hydrophilic Matrix Tablets for the Controlled Released of Chlorzoxazone.

International journal of molecular sciences·2024
Same author

Temperature-Controlled Chain Dynamics in Polyimide Doped with CoCl<sub>2</sub> Probed Using Dynamic Mechanical Analysis.

Materials (Basel, Switzerland)·2024
Same author

Integrated Hemicellulose Extraction and Papermaking Fiber Production from Agro-Waste Biomass.

Polymers·2024
Same author

Development of Solid Lipid Nanoparticles for Controlled Amiodarone Delivery.

Methods and protocols·2023

Related Experiment Video

Updated: May 5, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.7K

Removal of Rifampicin and Rifaximin Antibiotics on PET Fibers: Optimization, Modeling, and Mechanism Insight.

Elena Fasniuc-Pereu1, Elena Niculina Drăgoi2, Dumitru Bulgariu3,4

  • 1Department of Environmental Engineering and Management, "Cristofor Simionescu" Faculty of Chemical Engineering and Environmental Protection, Gheorghe Asachi Technical University of Iaşi, 700050 Iaşi, Romania.

Polymers
|August 14, 2025
PubMed
Summary

Recycled polyethylene terephthalate (PET) fibers effectively adsorb rifampicin and rifaximin antibiotics from water. This sustainable method offers a promising solution for antibiotic removal and recovery, utilizing waste materials for environmental remediation.

Keywords:
adsorptionantibioticsartificial neural networksmechanismmodelingpolyethylene terephthalate fibers

More Related Videos

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
10:29

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

Published on: March 24, 2017

7.9K
Refined Murine Model of Idiopathic Pulmonary Fibrosis
07:51

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Published on: June 17, 2025

289

Related Experiment Videos

Last Updated: May 5, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
09:57

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

8.7K
A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis
10:29

A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

Published on: March 24, 2017

7.9K
Refined Murine Model of Idiopathic Pulmonary Fibrosis
07:51

Refined Murine Model of Idiopathic Pulmonary Fibrosis

Published on: June 17, 2025

289

Area of Science:

  • Environmental Science
  • Materials Science
  • Chemical Engineering

Background:

  • Antibiotic removal and recovery from aqueous media are critical environmental challenges.
  • Adsorption is a viable method if the adsorbent is stable, cost-effective, and efficient.
  • Polyethylene terephthalate (PET) waste presents an opportunity for developing novel adsorbents.

Purpose of the Study:

  • To investigate the use of mechanically processed PET fibers as an adsorbent for rifampicin (RIF) and rifaximin (RIX) antibiotics.
  • To determine optimal adsorption conditions and understand the adsorption mechanism.
  • To evaluate the potential of PET fibers for practical antibiotic removal applications.

Main Methods:

  • Synthesized PET fibers from recycled PET waste.
  • Conducted adsorption experiments varying pH, adsorbent dose, contact time, initial concentration, and temperature.
  • Utilized a neuro-evolutive technique (ANE) combining deep learning (DL) and differential evolution for data analysis and model optimization.

Main Results:

  • PET fibers demonstrated effective adsorption of RIF and RIX, with adsorption capacities up to 7.6 mg/g (RIF) and 3.6 mg/g (RIX).
  • Adsorption followed Langmuir and pseudo-second-order kinetic models, indicating spontaneous and endothermic processes (ΔG < 0, ΔH > 0).
  • Physicochemical interactions governed RIF and RIX retention; inorganic anions enhanced adsorption capacity by influencing water molecule ordering.

Conclusions:

  • Mechanically processed PET fibers are a promising, low-cost adsorbent for removing RIF and RIX from aqueous solutions.
  • The study elucidated the adsorption mechanism, supporting the practical application of this waste-to-resource strategy.
  • This approach contributes to sustainable water treatment and antibiotic pollution mitigation.