BioModels' Model of the Year 2023

Area of Science:

• Computational biology
• Systems biology
• Bioinformatics

Background:

• Mathematical modeling is essential for understanding complex biological systems and their regulatory mechanisms.
• Such models offer significant advantages for industrial applications and address key biological questions.
• The BioModels Model of the Year competition was created to acknowledge and promote innovative modeling research in life sciences.

Purpose of the Study:

• To recognize and showcase outstanding modeling research in life sciences by early-career researchers.
• To encourage the adoption of reproducibility and FAIR (Findable, Accessible, Interoperable, Reusable) principles in model sharing.
• To delineate the competition's criteria and present the award recipients and their contributions.

Main Methods:

• The study outlines the participation and selection criteria for the BioModels Model of the Year 2023 competition.
• It introduces the researchers who received awards.
• It provides a summary of the modeling contributions made by the award recipients.

Main Results:

• The competition successfully highlighted advanced modeling research from early-career scientists.
• Award recipients presented models offering critical insights into key biological processes.
• The initiative promoted the principles of reproducibility and FAIR data sharing.

Conclusions:

• Mathematical modeling is a powerful tool for advancing biological research, offering insights into fundamental processes.
• The award recipients' work demonstrates significant contributions to understanding cell division, protein stability, and cell fate determination.
• The BioModels competition effectively fosters reproducibility and FAIR data sharing among emerging researchers in computational biology.