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Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
Published on: March 16, 2022
Adenovirus Disease and Ocular Symptoms in Children: Diagnosis and Prognostic Considerations
Jannatul Fardous1, Arpita Goutam2,3, Tajrin Rahman2,3
1Department of Paediatric Nephrology, National Institute of Kidney Diseases & Urology (NIKDU), Dhaka 1207, Bangladesh.
Abstract:
Adenoviral infections significantly impact pediatric health, manifesting as respiratory, gastrointestinal, and ocular disorders. We report a 14-year-old male with adenoviral pharyngoconjunctival fever (PCF) complicated by subconjunctival hemorrhage and enlarged adenoids. The patient presented with high-grade fever, sore throat, bilateral conjunctivitis, and gastrointestinal symptoms, including vomiting and diarrhea. Initial laboratory findings suggested septicemia; however, an extended respiratory panel confirmed adenoviral infection. Notably, the patient also had left-sided undescended testes and scoliosis, raising questions about potential associations. This case underscores the complexity of adenoviral infections in children, highlighting the interplay of respiratory, gastrointestinal, and ocular symptoms. The presence of additional conditions warrants further investigation into possible correlations with adenoviral infection. Comprehensive evaluation is crucial for accurate diagnosis and management of adenoviral infections in pediatric patients, and future research should explore long-term implications and associations with cryptorchidism and scoliosis.
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