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Updated: Sep 11, 2025

Author Spotlight: Illuminating New Avenues for Adipose Tissue Metabolism and Disease Prevention
Published on: October 6, 2023
Mechanomedicine targeting brown adipose tissue for metabolic health
Hui Yang1, Shanshan Zhu2, Zhe Yang3
1Department of Endocrinology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, PR China; The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University, Xi'an 710049, PR China; Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, PR China; Department of Gastroenterology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), NO. 19, Xiuhua St, Xiuying Dis, Haikou, Hainan, 570311, PR China.
Abstract:
Brown adipose tissue (BAT) is a compelling therapeutic target against metabolic diseases. Mechanical cues regulate BAT function and may offer novel, non-pharmacological therapeutic approaches. Herein, we discuss the biomechanical pathways underlying BAT activation, highlight advances in mechanotherapeutic strategies, and consider how emerging technologies may enhance these interventions.
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