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Solitary Neurofibroma in Lower Lip - A Case Report
Masashi Iwamoto1, Masato Narita2, Ichiro Wakita1
1Department of Oral Pathobiological Science and Surgery, Tokyo Dental College.
The Bulletin of Tokyo Dental College
|August 17, 2025
Summary
A rare case of solitary neurofibroma, a benign nerve sheath tumor, was found in a 59-year-old man's lower lip. Surgical removal was successful, with no recurrence after 1.5 years.
Area of Science:
- Oral and Maxillofacial Pathology
- Neurosurgery
- Oncology
Background:
- Solitary neurofibromas are benign peripheral nerve sheath tumors.
- These tumors are rare in the orofacial region, particularly the lip.
Purpose of the Study:
- To report a rare case of solitary neurofibroma in the lower lip.
- To discuss the clinical presentation, diagnosis, and management of this condition.
Main Methods:
- A 59-year-old male patient presented with a lower lip mass.
- Diagnostic imaging (MRI) and histopathological examination were performed.
- Surgical excision under general anesthesia was conducted.
Main Results:
- Histopathology confirmed a solitary neurofibroma.
- The patient experienced no recurrence 1.5 years post-surgery.
- Long-term follow-up is planned.
Conclusions:
- Solitary neurofibroma is a rare but treatable cause of lower lip masses.
- Surgical excision is an effective treatment.
- Regular follow-up is essential for monitoring.
