[Contractile function of the myocardium and oxygen metabolism in diabetes mellitus]

Myocardial contractility was studied by the radionuclide cardiography method and oxygen exchange and ABB by Astrup's method in 42 patients with insulin dependent and 50 patients with insulin independent diabetes mellitus. Indicators of tissue oxygenation and hemodynamics were correlated in both types of diabetes mellitus. At the start of disease tissue hypoxia causes compensatory change of hemodynamics, and the hyperkinetic type of the disease develops. Further development of diabetes mellitus results in disorder of myocardial contractility and deterioration of tissue oxygenation.