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Updated: Sep 11, 2025

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
From Cells to Strands: A Systematic Review Comparing Exosome Therapy, Platelet-Rich Plasma, and Minoxidil for
Rajah Darwish1, Marina Zakhary2, Kaleigh Wingate2
1Department of Dermatology, Florida State University College of Medicine, Tallahassee, USA.
Abstract:
Androgenetic alopecia (AGA) is a prevalent condition that significantly impacts psychological well-being and quality of life. Traditional therapies such as minoxidil and platelet-rich plasma (PRP) offer varying degrees of success, while exosome therapy has recently emerged as a potential alternative. This review compares the effectiveness, safety, and patient-centered outcomes of exosome therapy, PRP, and minoxidil in the management of AGA. The findings suggest that exosome therapy shows the most promising results in terms of hair regrowth and safety, followed by PRP, which offers moderate benefits. Minoxidil remains the most accessible treatment, though with more limited effectiveness and the need for continuous use. Overall, exosome therapy appears to hold the greatest potential for long-term improvement. Further research is needed to guide clinical decision-making and optimize treatment outcomes.

