Treatment charges for acute coronary syndrome: A retrospective analysis

Luke Frizzell1, Jonathan Deleon1, Sean Reilly1

  • 1Texas A&M University College of Medicine, Temple, Texas, USA.

Proceedings (Baylor University. Medical Center)
|August 18, 2025
PubMed

Insights

Coronary artery bypass grafting (CABG) has higher total costs than percutaneous coronary intervention (PCI) due to longer hospital stays, but lower daily charges. Reducing length of stay (LOS) is key for managing CABG costs and readmissions.

Area of Science:

  • Cardiovascular Medicine
  • Health Economics

Background:

  • Acute coronary syndrome (ACS) treatment involves strategies like coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI), and medical management (MM).
  • Previous analyses indicated superior outcomes with CABG over PCI and MM.

Purpose of the Study:

  • To analyze cost variations in ACS treatment based on strategy (CABG vs. PCI), hospital length of stay (LOS), and readmission rates.
  • To identify key drivers of total charges and daily expenses for different ACS treatment pathways.

Main Methods:

  • A substudy utilizing electronic health records from 4267 ACS patients (2018-2022).
  • Extraction of total reimbursements, LOS, and readmission data for CABG, PCI, and MM cohorts.
  • Comparative cost analysis focusing on total charges, daily charges, LOS, and readmission impact.

Main Results:

  • CABG patients incurred higher total charges than PCI patients (+$106,047), primarily driven by an 8.35-day longer LOS.
  • Despite higher total costs, CABG patients had lower average daily charges than PCI patients (+$14,957).
  • Readmissions increased total charges by an average of $22,765 ± $11,820, though daily charges remained lower due to extended LOS.

Conclusions:

  • Higher total costs for CABG and readmissions underscore the need for strategies to reduce LOS.
  • Optimizing LOS and minimizing charges associated with CABG and readmissions are crucial for cost-effective ACS management.
Abstract

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