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Current applications and future perspectives on rare-earth-based materials in stomatology
Zhirao Dong1, Xinyue Lu1, Weiyu Zhang1
1Department of Orthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, P.R. China.
Rare earth elements (REEs) offer advanced properties for novel oral materials, addressing limitations in current dental treatments. This review explores REE applications to improve oral healthcare diagnostics and therapies.
Area of Science:
- Biomaterials Science
- Dental Materials
- Nanotechnology
Background:
- Conventional dental materials face challenges like poor biocompatibility and limited functionality.
- Current stomatology struggles with precise diagnosis and effective treatment due to material limitations.
Purpose of the Study:
- To review the physicochemical properties and biological functions of rare earth elements (REEs).
- To provide a comprehensive overview of cutting-edge applications of rare-earth-based materials in oral medicine.
- To highlight the interdisciplinary value of REEs in advancing stomatology and oral healthcare.
Main Methods:
- Literature review of rare earth elements' properties and applications.
- Analysis of REE-based materials in the context of oral healthcare demands.
- Synthesis of current knowledge on REE functionalities for dental applications.
Main Results:
- REEs possess unique electronic configurations and multivalent properties.
- REEs exhibit excellent optical response, enzyme simulation, antibacterial efficacy, and biological regulation.
- These properties make REEs promising for developing next-generation oral functional materials.
Conclusions:
- Rare-earth-based materials present a significant opportunity to overcome limitations in contemporary stomatology.
- Further research into REEs can lead to improved diagnostic tools and therapeutic strategies in dentistry.
- This review underscores the potential of REEs to revolutionize oral healthcare.

