Related Experiment Video
Updated: Sep 10, 2025

Brain Ventricular Microinjections of Lipopolysaccharide into Larval Zebrafish to Assess Neuroinflammation and Neurotoxicity
Published on: August 23, 2022
Antibiotics unleash neuroinflammation
Jessica E Kenison1,2,3, Francisco J Quintana1,2,3
1Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School , Boston, MA, USA.
Abstract:
The gut microbiome limits neuroinflammation and neurocognitive decline in acute graft-versus-host disease by modulating microglial activation via a mechanism mediated by the microbial metabolite TMAVA (Chatterjee et al. https://doi.org/10.1084/jem.20242180).
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