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Updated: Sep 10, 2025

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
07:11

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography

Published on: October 28, 2020

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Prognostic value of right ventricular ejection fraction using three-dimensional echocardiography in patients with

Tetsuji Kitano1,2, Yasufumi Nagata3, Yosuke Nabeshima4

  • 1Department of Clinical Training and Career Support Center, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. syuukyuu1986@gmail.com.

Journal of Echocardiography
|August 19, 2025
PubMed

Insights

Three-dimensional echocardiography-derived right ventricular ejection fraction (RVEF) is a strong predictor of cardiac events in patients with ischemic and dilated cardiomyopathy. This measurement offers valuable risk stratification beyond traditional echocardiographic parameters.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiovascular Imaging

Background:

  • Limited data exists on the prognostic significance of three-dimensional echocardiography (3DE)-derived right ventricular ejection fraction (RVEF) in ischemic cardiomyopathy (ICM) and dilated cardiomyopathy (DCM).
  • Assessing RV function is crucial for managing heart failure patients.

Purpose of the Study:

  • To evaluate the prognostic value of 3DE-derived RVEF in patients with ICM and DCM.
  • To determine if RVEF provides incremental prognostic information beyond conventional echocardiographic measures.

Main Methods:

  • Retrospective analysis of 120 ICM and 107 DCM patients who underwent 3DE.
  • Utilized 3DE speckle tracking software for RVEF assessment.
  • Primary endpoint: composite of cardiac death, heart failure hospitalization, myocardial infarction, or ventricular tachyarrhythmia.

Main Results:

  • RVEF was significantly associated with cardiac events in both ICM and DCM groups (Univariate and Multivariable analysis).
  • RVEF demonstrated independent prognostic value after adjusting for clinical factors and LV parameters.
  • Kaplan-Meier analysis showed significant risk stratification based on RVEF and E/e' levels.

Conclusions:

  • 3DE-derived RVEF is an independent and incremental predictor of cardiac events in ICM and DCM.
  • RVEF, combined with E/e', allows for detailed risk stratification in these patient populations.
Abstract

Keywords:
Dilated cardiomyopathyIschemic cardiomyopathyOutcomesPrognosisRight ventricular ejection fractionThree-dimensional echocardiography

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