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[Colonoscopy in infants: procedure and disease spectrum analysis of 184 cases]
Xiao-Li Fu1, Xu-Xia Wei1, Jun-Jie Xu1
1Department of Gastroenterology, Children's Hospital Affiliated to Shandong University/Jinan Children's Hospital, Jinan 250022, China.
Insights
Colonoscopy is vital for diagnosing infant digestive issues. The study found that causes for the procedure and the spectrum of diseases diagnosed varied significantly by infant age and examination period.
Area of Science:
- Pediatric Gastroenterology
- Diagnostic Endoscopy
Objectives:
To investigate the underlying causes and clinical manifestations in infants undergoing colonoscopy, and to analyze changes in disease spectrum.
Methods:
Clinical data from 180 infants who underwent a total of 184 colonoscopies at the Department of Gastroenterology, Children's Hospital Affiliated to Shandong University from January 2015 to December 2024 were retrospectively analyzed. Patients were grouped by age: ≤6 months (n=41) and >6-12 months (n=139); and by examination period: 2015-2019 (n=83) and 2020-2024 (n=97). Primary causes for performing colonoscopy, final diagnoses, and disease spectrum evolution were assessed.
Results:
Among 184 colonoscopies, the leading causes prompting examination were hematochezia (37.8%, 68/180), diarrhea (36.7%, 66/180), and co-occurring hematochezia and diarrhea (21.1%, 38/180). Causes for performing colonoscopy differed significantly by age group (P<0.05). Colonic polyps were only detected in the >6-12 months group (P<0.05). Compared to the 2015-2019 group, the 2020-2024 group had fewer food allergy-related gastrointestinal diseases (P<0.05) but more colitis (P<0.05).
Conclusions:
Colonoscopy is essential for diagnosing infantile digestive disorders, with disease spectra varying by age and time period.
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