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Updated: Sep 10, 2025
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
[Development of a quality control indicator system for neonatal screening of inherited metabolic diseases in
Hui Li1, Jin Zhang1, Dan-Feng Cao1
1Department of Nursing, The First Affiliated Hospital of Shandong First Medical University ＆ Shandong Province Qianfoshan Hospital, Jinan 250014, China.
Insights
A new quality control indicator system was developed for neonatal screening of inherited metabolic diseases in obstetric settings. This system offers a standardized tool for improving the quality of clinical screening programs.
Area of Science:
- Medical Science
- Public Health
- Clinical Diagnostics
Objectives:
To develop a quality control indicator system for neonatal screening of inherited metabolic diseases in obstetric settings, so as to provide a standardized tool for quality control in clinical neonatal screening of inherited metabolic diseases.
Methods:
From March to May 2024, a literature review combined with expert clinical experience was conducted to develop a preliminary questionnaire on quality control indicators for neonatal screening of inherited metabolic diseases. The final indicator system was established after two rounds of the Delphi method, and the Analytic Hierarchy Process was used to determine indicator weights.
Results:
Sixteen questionnaires were distributed in each of the two consultation rounds, with a valid response rate of 100% for both. The expert authority coefficients were 0.863 and 0.876, respectively. Kendall's coefficient of concordance for the importance and feasibility of the indicators ranged from 0.091 to 0.125. The final indicator system comprised 3 primary indicators, 8 secondary indicators, and 28 tertiary indicators for neonatal screening of inherited metabolic diseases in obstetric settings.
Conclusions:
The quality control indicator system developed using the Delphi method demonstrates a strong systematic structure, high clinical adaptability, and strong operability, and can be effectively applied to quality control in neonatal screening of inherited metabolic diseases in obstetric settings.
