Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bacterial Phylum Bacteroidota01:26

Bacterial Phylum Bacteroidota

121
The phylum Bacteroidota includes over 700 species classified into four primary orders: Bacteroidales, Cytophagales, Flavobacteriales, and Sphingobacteriales. These gram-negative, non-sporulating rods exhibit saccharolytic capabilities and can be aerobic or fermentative, encompassing obligate aerobes, facultative aerobes, and obligate anaerobes. Many species display gliding motility, though some are nonmotile or use flagella. The genus Bacteroides is well-studied due to its significant role in...
121
Bacterial Phylum Firmicutes01:27

Bacterial Phylum Firmicutes

142
Firmicutes is a diverse phylum of Gram-positive bacteria characterized by a low GC content in their genomes. This phylum includes organisms with monoderm or diderm cell envelopes, highlighting a complex evolutionary history. Firmicutes comprises several major orders, including Lactobacillales, Clostridiales, and Bacillales, which exhibit remarkable diversity in their morphology, metabolism, and ecological roles.The order Lactobacillales includes lactic acid bacteria, which are fermentative...
142
Bacterial Phylum Proteobacteria01:26

Bacterial Phylum Proteobacteria

130
Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...
130
Infection01:20

Infection

8.7K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
8.7K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

12.2K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.2K
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

110
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
110

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Supramolecular strategy for compartment pathogen clearance and immuno-metabolic homeostasis to treat periodontitis.

Nature communications·2026
Same author

Design and Performance Study of a Compliant Mechanism Capable of Achieving Dual-Range Constant Force Output.

Micromachines·2026
Same author

Epidemiological and Genomic Characterization of Japanese Encephalitis Virus in Mosquitoes in China.

Journal of medical virology·2026
Same author

B-Cell Landscape in Inflamed Dental Pulp Reveals Potential Autoimmune Involvement.

Journal of dental research·2026
Same author

Intra-host GI.1 norovirus evolution is shaped by genetic drift and purifying selection.

Virus evolution·2026
Same author

Genetic diversity and occurrence of antibiotic resistance genes from community wastewater in Dhaka and Cox's Bazar, Bangladesh.

One health (Amsterdam, Netherlands)·2026

Related Experiment Video

Updated: Sep 8, 2025

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
12:16

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Published on: December 17, 2015

26.5K

Fretibacterium: Exploring Its Pathogenic Potential in Oral Infectious Diseases.

Lisha Liang1, Pengbo Liu1, Dongzhe Song1,2

  • 1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Molecular Oral Microbiology
|August 20, 2025
PubMed
Summary
This summary is machine-generated.

Fretibacterium, a key oral bacterium, is increasingly linked to periodontal disease and other infections. Understanding its role and virulence is crucial for developing new treatments for oral and systemic conditions.

Keywords:
FretibacteriumFretibacterium fastidiosumoral infectious diseasesperiodontitisphylum synergistetes

More Related Videos

Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro
08:41

Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro

Published on: March 28, 2025

811
Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi
12:33

Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi

Published on: July 6, 2016

9.7K

Related Experiment Videos

Last Updated: Sep 8, 2025

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells
12:16

Porphyromonas gingivalis as a Model Organism for Assessing Interaction of Anaerobic Bacteria with Host Cells

Published on: December 17, 2015

26.5K
Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro
08:41

Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro

Published on: March 28, 2025

811
Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi
12:33

Determination of Biofilm Initiation on Virus-infected Cells by Bacteria and Fungi

Published on: July 6, 2016

9.7K

Area of Science:

  • Microbiology
  • Oral Health
  • Periodontology

Background:

  • Oral infectious diseases, especially periodontal lesions, significantly impact global health and economies.
  • Oral microbiome dysbiosis is a primary driver of oral infectious diseases.
  • Fretibacterium, a strictly anaerobic genus, shows enrichment in periodontitis, highlighting its disease association.

Purpose of the Study:

  • To review the role of Fretibacterium in various oral infections.
  • To examine Fretibacterium's virulence mechanisms and clinical associations.
  • To evaluate current and novel therapeutic strategies for Fretibacterium-associated conditions.

Main Methods:

  • Literature review synthesizing current knowledge on Fretibacterium.
  • Analysis of Fretibacterium's involvement in periodontal disease, dental caries, endodontic infections, and peri-implantitis.
  • Exploration of clinical associations with systemic diseases and therapeutic interventions.

Main Results:

  • Fretibacterium is progressively enriched in periodontitis, with distinct abundance in health versus disease states.
  • The review details Fretibacterium's virulence factors and its association with systemic conditions like diabetes.
  • Both conventional and emerging therapeutic strategies are evaluated.

Conclusions:

  • Fretibacterium plays a significant role in oral infectious diseases, including periodontitis.
  • Understanding Fretibacterium's mechanisms and associations is vital for clinical management.
  • This review provides evidence-based insights to guide future research and treatment approaches.