Related Experiment Video
Updated: Sep 10, 2025
Intradermal Inoculation of Mycobacterium avium in the Mouse Ear
Published on: July 3, 2025
Chronic rhinitis associated with Mycobacterium avium infection: A CARE case report
J-P Martellosio1, L Deroche2, M Garcia3
1Service de Médecine Interne, Centre Hospitalier Universitaire de Poitiers, 2, rue de la Milétrie, 86000 Poitiers, France.
Introduction:
Nasal infection caused by Mycobacterium avium is rare and is a diagnostic challenge due to the non-specific symptoms and absence of pathognomonic signs.
Case Report:
We report the case of a 72-year-old patient with chronic rhinitis persisting for 4years and refractory to conventional treatments. ENT examination revealed irregular nasal mucosa with an inflammatory nasopharyngeal polyp. Histological analysis showed epithelioid granuloma, and Ziehl-Neelsen staining highlighted acid-fast bacilli. Mycobacterial culture confirmed M. avium infection. Treatment with rifampin, azithromycin and ethambutol led to significant clinical improvement, with resolution of local inflammation.
Discussion:
Nasal infection by M. avium is exceptional, with only a few cases reported in the literature. Diagnosis relies on histological examination and mycobacterial culture. Treatment combines surgical resection of the polypoid tumor and prolonged antibiotic therapy.
Conclusion:
M. avium infection should be considered in cases of atypical chronic rhinitis resistant to treatment. Thorough microbiological evaluation is essential for accurate diagnosis and appropriate management.
Related Concept Videos
01:28Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:29Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:23Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
01:31Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:28Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...