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Updated: Sep 10, 2025

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.4K

"Acute coronary syndrome with atypical ST segment elevation may underlie multivessel coronary artery disease"

Michele Correale1, Davide Manfredi2, Maria Luigia Tucci2

  • 1Cardiothoracic Department, Policlinico Riuniti University Hospital, Foggia, Italy.

Journal of Electrocardiology
|August 21, 2025
PubMed

Insights

Atypical ST elevation in acute coronary syndrome can indicate multivessel coronary disease. Early diagnosis via angiography and prompt angioplasty are crucial for effective treatment.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Medical Diagnostics

Background:

  • Acute coronary syndrome (ACS) can present with atypical electrocardiogram (ECG) findings.
  • Single-lead ST elevation, ST depression, and T-wave inversions may suggest complex coronary artery disease.

Purpose of the Study:

  • To report a rare case of ACS with atypical ECG manifestations.
  • To highlight the association between these ECG findings and multivessel coronary artery disease.

Main Methods:

  • Case report of an elderly male patient presenting with syncope and epigastric pain.
  • Analysis of high-sensitivity troponin I (hs-TnI) levels and ECG findings, specifically ST-segment elevation in lead V3.
  • Coronary angiography to assess coronary artery anatomy.

Main Results:

  • The patient exhibited pronounced ST-segment elevation in lead V3, atypical for ACS.
  • Coronary angiography revealed significant multivessel coronary artery disease.
  • The patient successfully underwent coronary angioplasty.

Conclusions:

  • Atypical ST elevation patterns in ACS, particularly in specific leads like V3, warrant thorough investigation for multivessel coronary artery disease.
  • Prompt diagnostic angiography and revascularization are vital in managing such complex cases.

Keywords:
Acute coronary syndromeAtypical electrocardiogramMultivessel coronary artery diseaseST-elevation acute myocardial infarctionsyncope

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