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Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

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Evidence-Generated Sockets for Transtibial Prosthetic Limbs Compared With Conventional Computer-Aided Designs: A

Florence Mbithi¹, Maggie Donovan-Hall¹, Jennifer Bramley²

¹Mechanical Engineering Department, University of Southampton, Mailpoint M7, University Road, Highfield, Southampton, SO17 1BJ, United Kingdom, 44 2380595394.

JMIR Rehabilitation and Assistive Technologies

|August 21, 2025

Summary

This summary is machine-generated.

Evidence-generated prosthetic sockets offer comparable comfort to traditional methods, reducing design time and enhancing prosthetist customization. This innovation supports better patient outcomes in prosthetic limb fitting.

Keywords:

CAD/CAM computer aided design and manufacturing evidence-based practice prosthetic socket design qualitative research transtibial

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A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study

Published on: November 6, 2015

Area of Science:

Prosthetics and Orthotics
Biomedical Engineering
Rehabilitation Science

Background:

Personalized prosthetic socket design relies on skilled prosthetists balancing function, comfort, and load transmission.
Current methods (plaster, CAD/CAM) are iterative, hindering knowledge sharing.
Evidence-generated (EG) sockets, using past computer-aided socket design (CASD) records, offer a personalized starting point for prosthetic fitting.

Purpose of the Study:

To assess the comfort of evidence-generated (EG) prosthetic sockets derived from previous CASD records.

Main Methods:

A crossover trial compared EG sockets with conventional clinician-led CAD/CAM sockets in 17 participants with 19 transtibial amputations across 3 UK NHS clinics.
Noninferiority of socket comfort score (SCS) was the primary outcome.
Semistructured interviews were conducted for in-depth user analysis.

Main Results:

EG sockets showed no statistically significant difference in comfort compared to clinician-led control sockets (median SCS 8.6 vs. 8.8).
EG sockets exhibited lower variability in SCS across participants.
Qualitative analysis revealed themes on fitting experiences, socket comparisons, and residual limb factors influencing comfort.

Conclusions:

EG sockets are noninferior to conventional CASD practice for socket comfort.
Clinician input remains essential and highly valued by prosthesis users.
Future work aims to integrate EG sockets into CASD software as a digital starting point for expert clinician modification, optimizing customization and co-design.