Intralesional Cryosurgery for Resistant Ear Keloids: Clinical Efficacy and Patient Experience

Keloids are fibrotic scars prone to recurrence, and managing resistant ear keloids remains challenging. Conventional therapies often yield limited success, necessitating alternative approaches. Intralesional (IL) cryosurgery delivers targeted tissue necrosis with minimal epidermal damage, making it a promising option for refractory cases.

This study aimed to evaluate the efficacy, tolerability, and patient satisfaction of IL cryosurgery in the treatment of resistant ear keloids.

This retrospective study included 37 patients with 49 ear keloids, all of whom had previously undergone at least 1 unsuccessful treatment. IL cryosurgery was performed in up to 4 sessions or until a ≥80% reduction in keloid size was achieved. Treatment response was assessed using standardized digital images reviewed by an independent dermatologist. Patient satisfaction was measured with a 5-point Likert scale. All patients were followed for at least 6 months after the final treatment session to assess recurrence.

A reduction in keloid size by ≥50% was observed in 46 out of 49 lesions (94.0%), with 31 of these lesions (63.3%) achieving ≥80% reduction. During 6-month follow-up, recurrence was observed in 3 keloids (6.1%) across 2 patients. Patient satisfaction scores were high across all parameters, including overall satisfaction, perceived size reduction, symptom relief, procedural comfort, and willingness to undergo treatment again. No severe adverse effects were reported.

IL cryosurgery is an effective, safe, and well-tolerated treatment for resistant ear keloids. Further studies are needed to confirm its long-term efficacy.