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The evolving imaging of rapidly improving posterior reversible encephalopathy syndrome: A case report
Yilong He1, Langtao He2, Yetao Lin3
1Department of Neurology, Longhua Branch of Shenzhen People's Hospital, Shenzhen, China.
Abstract:
Posterior reversible encephalopathy syndrome (PRES) is a rare neurological disorder with no specific clinical symptoms in the early stage; thus, early imaging identification is of great importance. A 29-year-old pregnant woman at 37 weeks experienced sudden generalized seizures accompanied by impaired consciousness. Brain computed tomography, conducted around 3 h after the onset, revealed symmetric areas of decreased density in the basal ganglia, brainstem, and suboccipital cortex, along with cerebral swelling. Following treatment with positive inotrope, diuretics, antihypertensives, and dehydration therapy, the patient regained clear consciousness on the 2nd day. On the 9th day postonset, a follow-up contrast-enhanced magnetic resonance imaging (MRI) showed slightly elevated signals in the bilateral occipital lobes on the T2 fluid-attenuated inversion recovery sequence. A subsequent brain MRI on day 47 postonset indicated no significant abnormal changes. Neuroimaging is pivotal for PRES diagnosis, revealing typical signs of widespread vasogenic edema in the posterior brain white matter, affecting the occipital lobes, cerebellum, brainstem, thalamus, and basal ganglia. With timely treatment, these lesions can partially or completely resolve within days or weeks.
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