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Updated: Sep 10, 2025

Author Spotlight: Advancements in Synthetic Genetic Devices for Stem Cell Fate Manipulation and Cellular Therapy Development
Published on: December 8, 2023
Advancing cell therapies with artificial intelligence and synthetic biology
Mahima Choudhury1, Annika J Deans2, Daniel R Candland1
1Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.
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Artificial intelligence provides an exciting avenue to improve approaches in cell therapies by learning and predicting dynamic gene expression patterns from large datasets of stem cell differentiation. The integration of synthetic biology provides genetic tools that mimic the spatial and temporal expression patterns during differentiation, enhancing the potential to significantly improve differentiation outcomes and further our understanding of the mechanisms involved during cell fate decisions.
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