Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemispheric disconnection and rotational behaviour.

M Mintz, R Douglas, L Kellaway

    Behavioural Brain Research
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Safety and Efficacy of Atezolizumab in Combination With nab-Paclitaxel in Patients With PD-L1 Positive Metastatic or Locally Advanced Triple-Negative Breast Cancer: A UK-Wide Cancer Centre Experience.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2025
    Same author

    Combining QSAR and SSD to predict aquatic toxicity and species sensitivity of pyrethroid and organophosphate pesticides.

    SAR and QSAR in environmental research·2024
    Same author

    Position paper on olfactory dysfunction: 2023

    Rhinology·2023
    Same author

    Towards an action plan for characterizing food plant diversity.

    Nature plants·2022
    Same author

    Seeking graduation in medical colleges outside India: Is it a 'win-win' or 'lose-lose' situation for the stakeholders and the nation?

    The National medical journal of India·2022
    Same author

    A historical review of the evolution of nasal lavage systems.

    The Journal of laryngology and otology·2021
    Same journal

    Central administration of oxytocin increases social interaction and shoaling behaviour in guppies.

    Behavioural brain research·2026
    Same journal

    TAK-242 has sex-dependent effects on the acquisition of two-way active avoidance conditioning.

    Behavioural brain research·2026
    Same journal

    Fear conditioning with five footshocks is sufficient to produce stress-enhanced fear learning in rats but does not produce physiological characteristics of stress.

    Behavioural brain research·2026
    Same journal

    Behavioral characterization of bulbar sensorimotor function in a rat model of Alexander disease.

    Behavioural brain research·2026
    Same journal

    Prenatal exposure to high- but not low-molecular-weight poly(I:C) produces selective sociability deficits in offspring.

    Behavioural brain research·2026
    Same journal

    Understanding vulnerability through variability: a longitudinal twin study linking sex differences in neurodiversity, neurodevelopment and X-linked genetic mechanisms.

    Behavioural brain research·2026
    See all related articles

    The thalamus does not control interhemispheric nigrostriatal function. Midsagittal thalamic transection in rats did not alter amphetamine-induced rotation, suggesting crossed pathways bypass the thalamus.

    Area of Science:

    • Neuroscience
    • Neuroanatomy

    Background:

    • The extrapyramidal system exhibits crossed pathways between hemispheres.
    • The role of the thalamus in interhemispheric control of nigrostriatal function is not fully understood.

    Purpose of the Study:

    • To investigate the thalamus's role in interhemispheric control of nigrostriatal function.
    • To determine if the thalamus is a crucial relay for crossed nigrostriatal pathways.

    Main Methods:

    • Midsagittal thalamic transection in rats.
    • Assessment of amphetamine-induced rotational behavior.
    • Lesioning of the substantia nigra.
    • Retrograde tracing using horseradish peroxidase.

    Main Results:

    • Thalamic transection did not affect net rotational asymmetry or amphetamine-induced rotation.

    Related Experiment Videos

  • Subsequent substantia nigra lesions did not alter rotational asymmetry post-transection.
  • Retrograde labeling of substantia nigra and ventral tegmental area neurons was not interrupted by thalamic transection.

    • Conclusions:

    • The thalamus does not appear to mediate interhemispheric control of nigrostriatal asymmetry.
    • Crossed nigrostriatal projections do not decussate via the thalamus.
    • Pathway crossing likely occurs in the ventral mesencephalon.