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Updated: Sep 10, 2025
Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
Published on: January 15, 2022
Prognostic Value of Intravascular Optical Coherence Tomography in Patients With Coronary Heart Disease Undergoing
Zhengya Fang1, Suwen Zhu1, Shaodong Zhang1
1Department of Cardiovascular Medicine, Liyang People's Hospital, Liyang, China.
Objective:
We aimed to ascertain the predictive value of intravascular optical coherence tomography (OCT) in the prognosis of coronary heart disease (CHD) patients undergoing percutaneous coronary intervention (PCI).
Methods:
Independent factors affecting major adverse cardiac events (MACE) and predictive efficacy of OCT parameters on MACE in CHD patients were analyzed.
Results:
Advanced age and large lipid arc degree were risk factors for MACE occurrence (OR > 1, p < 0.05), while thick fibrous cap thickness and high left ventricular ejection fraction were protective (OR < 1, p < 0.05). Fibrous cap thickness predicted MACE (AUC 0.765, 95% CI 0.690 ~ 0.840, cut-off 92 μm); lipid arc degree did as well (AUC 0.885, 95% CI 0.817 ~ 0.952, cut-off 214.5°).
Conclusion:
OCT supports interventional treatment in CHD patients, with fibrous cap thickness and lipid arc degree demonstrating some prognostic predictive value post-PCI.
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