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CHASHNIt for enhancing skin disease classification using GAN augmented hybrid model with LIME and SHAP based XAI
Saksham Anand1, Abhiram Sharma1, B Natarajan2
1School of Computer Science and Engineering, Vellore Institute of Technology, Chennai, 600127, India.
Scientific Reports
|August 24, 2025
Summary
A new hybrid deep learning model, CHASHNIt, significantly improves skin disease classification accuracy. It uses GANs for data augmentation and explainable AI for transparency, achieving 97.8% accuracy.
Area of Science:
- Dermatology
- Artificial Intelligence
- Medical Imaging
Background:
- Accurate skin disease classification is crucial for timely diagnosis.
- Deep learning models face challenges like data imbalance and lack of interpretability in medical applications.
Purpose of the Study:
- To introduce CHASHNIt, a novel hybrid deep learning model integrating EfficientNetB7, DenseNet201, and InceptionResNetV2.
- To enhance skin disease classification by addressing data imbalance and improving model interpretability.
Main Methods:
- Utilized Generative Adversarial Networks (GANs) for data augmentation to ensure balanced class representation.
- Implemented sophisticated preprocessing techniques including normalization and feature selection.
- Integrated Explainable AI (XAI) methods like SHAP and LIME for model transparency.
Main Results:
- Achieved high performance metrics: 97.8% accuracy, 98.1% precision, 97.5% recall, 97.6% F1 Score, and 92.3% IoU.
- Outperformed benchmark models including Swin Transformer, ResNet101, and ConvNeXt.
- Ablation studies confirmed the synergistic benefits of the hybrid architecture.
Conclusions:
- CHASHNIt offers an advanced, automated framework for skin disease classification, balancing scalability, accuracy, and explainability.
- The model demonstrates superior performance and transparency compared to existing methods.
- Future work will focus on optimizing computational efficiency for low-resource devices.

