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[Cutaneous leishmaniasis in northern Algeria].
Bulletin De La Societe De Pathologie Exotique Et De Ses Filiales
|January 1, 1985
Summary
A resurgence of cutaneous leishmaniasis in Algeria is linked to the Leishmania donovani complex. Preliminary clinical trial results show ketoconazole is a rapidly effective treatment for this oriental sore.
Area of Science:
- Infectious Diseases
- Parasitology
- Dermatology
Context:
- Cutaneous leishmaniasis is re-emerging in northern Algeria.
- This outbreak is associated with the Leishmania donovani complex, distinct from L. major.
- The oriental sore presents unique epidemiological and clinical features in this region.
Purpose:
- To identify the causative agent of the current cutaneous leishmaniasis resurgence in northern Algeria.
- To differentiate this outbreak from existing zoonotic cutaneous leishmaniasis.
- To evaluate the efficacy of ketoconazole as a treatment.
Summary:
- The resurgence of cutaneous leishmaniasis in northern Algeria is caused by a parasite within the Leishmania donovani complex.
- Epidemiological and clinical data distinguish it from L. major zoonotic cutaneous leishmaniasis prevalent in steppe regions.
- Preliminary findings from a clinical trial suggest ketoconazole demonstrates rapid effectiveness.
Impact:
- Provides crucial insights into the evolving epidemiology of leishmaniasis in Algeria.
- Highlights ketoconazole as a promising and effective therapeutic option.
- Informs public health strategies for controlling leishmaniasis resurgence.