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A Pilot Validation Study of a Biomechanical Simulation Model for Rotational Ankle Injuries Using Robotic Cadaveric
Mohammad Amin Shayestehpour1,2, Martin G Gregersen3,4, Ola Saatvedt5,6
1Department of Orthopaedic Surgery, Østfold Hospital Trust, Grålum, Norway.
Foot & Ankle Orthopaedics
|August 25, 2025
Summary
This study introduces a validated computer model to simulate deltoid ligament strain during rotational ankle injuries. The model accurately predicts injury progression and ligament behavior, offering new insights into ankle trauma mechanisms.
Area of Science:
- Biomechanics
- Orthopedic Surgery
- Computational Modeling
Background:
- Deltoid ligament injuries are linked to rotational ankle trauma.
- Existing understanding of injury sequences may be incomplete.
- Computer modeling presents a novel approach to assess ligament behavior.
Purpose of the Study:
- To develop and validate a biomechanical computer simulation model for rotational ankle injuries.
- To evaluate ligament strain patterns during simulated injuries.
- To provide a tool for understanding deltoid ligament biomechanics.
Main Methods:
- A biomechanical computer model was created using AnyBody Modeling Software.
- Cadaveric data from 15 human ankle specimens were used for parameter identification.
- The model simulated Supination-External Rotation (SER) stages 2-4b injuries and was validated against experimental data.
Main Results:
- The computer model demonstrated high correlation (0.81-0.99) with experimental findings.
- Progressive tension in the deep posterior tibiotalar ligament (DPTTL) was observed from SER2 to SER4a.
- The model accurately captured ligament strain progression and medial clear space changes.
Conclusions:
- An early-stage biomechanical simulation model for rotational ankle injuries has been developed and validated.
- This model serves as a novel tool for investigating ligament biomechanics and injury mechanisms.
- The model offers insights beyond cadaveric or clinical studies, aiding hypothesis generation and treatment refinement.

