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Isolated splenic sarcoidosis: A case report.

Coro Velasco Gametxogoikoetxea¹, Irene Fernández De Los Reyes², Fermín Jiménez Bermejo³

¹Servicio Navarro de Salud-Osasunbidea. Hospital Universitario de Navarra. Servicio de Cardiología. Pamplona. España.

Anales Del Sistema Sanitario De Navarra

|August 25, 2025

Summary

Isolated splenic sarcoidosis is rare but important to consider for prolonged fevers. This case highlights sarcoidosis diagnosis in a young patient with fever of unknown origin.

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Area of Science:

Internal Medicine
Pathology

Background:

Isolated splenic sarcoidosis is an uncommon condition.
Diagnosis can be challenging due to a wide differential diagnosis.

Observation:

A 15-year-old female presented with fever of unknown origin.
Histopathology revealed non-caseating and necrotizing granulomas.

Findings:

The patient was diagnosed with isolated splenic sarcoidosis.
Corticosteroid therapy led to significant clinical and radiological improvement.

Implications:

Sarcoidosis should be considered in the differential diagnosis of prolonged fever, especially in young patients.
This case underscores the importance of considering sarcoidosis in atypical presentations without respiratory symptoms.