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Published on: May 26, 2023
Risk Factors for One-Year Postdischarge Mortality: An Analysis From the World Database for Pediatric and Congenital
Brian P Bateson1, James D St Louis1, Sivakumar Sivalingam2
1Department of Surgery, Augusta University, Augusta, GA, USA.
This study analyzed one-year mortality in pediatric heart surgery patients using the World Database for Pediatric and Congenital Heart Surgery (WDPCHS). Key risk factors like STAT 5, chromosomal abnormalities, and multiple preoperative issues significantly increase mortality risk.
Area of Science:
- Pediatric Cardiology
- Cardiac Surgery
- Public Health
Background:
- The World Database for Pediatric and Congenital Heart Surgery (WDPCHS) is a critical resource for understanding outcomes in pediatric and congenital heart surgery.
- Defining one-year mortality incidence and identifying associated risk factors is crucial for improving patient care and surgical strategies.
Purpose of the Study:
- To determine the incidence of one-year mortality after congenital heart disease surgery.
- To identify significant preoperative and postoperative risk factors associated with one-year mortality.
Main Methods:
- Utilized data from the WDPCHS database between January 2017 and September 2022 for tier 1 surgeries.
- Defined out-of-hospital death as occurring between 30 days and one year postoperatively.
- Employed chi-square tests and multivariable logistic regression to analyze risk factors and associations.
Main Results:
- Overall one-year mortality was 1.47% among 9764 patients alive at hospital discharge.
- Highest mortality rates were observed in STAT 5 cases (22.88%) and following the Norwood procedure (22.88%).
- Significant risk factors for one-year mortality included non-Trisomy 21 genetic syndromes, multiple preoperative risk factors, and multiple postoperative complications.
Conclusions:
- Specific risk factors, including STAT 5 classification, non-Trisomy 21 chromosomal abnormalities, and multiple preoperative risk factors, are strongly associated with increased one-year mortality.
- Targeted surveillance for patients with these identified risk factors is recommended to enhance one-year outcomes.
- The WDPCHS provides valuable data for identifying critical risk factors in congenital heart surgery.
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