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Light-responsive coumarin-functionalised nanogels for metformin delivery

Hend A M Abdelmohsen1, David L Rochester2, Algy Kazlauciunas3

  • 1Department of Chemistry, Faculty of Science and Technology, Lancaster University, Lancaster, Lancashire LA1 4YB, UK; Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster, Lancashire LA1 4YW, UK; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ain Shams University, African Union Organization Street, Abbassia, Cairo 11566, Egypt.

International Journal of Pharmaceutics
|August 26, 2025
PubMed
Summary

A novel light-responsive nanogel system delivers metformin to treat corneal neovascularization. This minimally invasive approach offers a promising alternative to repeated injections for severe ocular diseases.

Keywords:
Light-responsiveLight-triggeredOcular drug deliveryPhotochemistryStimuli-responsive

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