Related Experiment Video
Updated: Sep 10, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
Published on: February 16, 2024
Initial misdiagnosis of gastritis cystica profunda: Two case reports
Xiao-Li Zheng1, Long Xu2, Jun Wang3
1Department of Gastroenterology, Shenzhen University General Hospital, Shenzhen 518000, Guangdong Province, China.
Background:
Gastritis cystica profunda (GCP) is a rare gastric disorder. It is characterized by non-specific symptoms and diagnostic complexity. This case report enriches the medical literature by highlighting challenges in diagnosing and treating GCP.
Case Summary:
Two patients presented with non-specific abdominal symptoms, such as abdominal distension and epigastric discomfort. Initial misdiagnosis occurred due to GCP's non-typical manifestations. After thorough investigations, GCP was diagnosed. Endoscopic mucosal resection and endoscopic submucosal dissection were carried out. Both patients recovered uneventfully.
Conclusion:
GCP diagnosis demands caution, and endoscopic treatment is effective.
Related Concept Videos
Gastritis-I: Introduction and Types
Acute gastritis presents as a sudden inflammation triggered by various stressors to the stomach lining, such as exposure to corrosive agents, local irritants like aspirin and other NSAIDs, alcohol consumption, radiation therapy, physical trauma, severe burns, sepsis,...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Other Disorders of Digestive System
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...

