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Quantitative Pharmacokinetic Mapping with AI: Toward More Generalizable Response Prediction in Breast Cancer MRI

Tician Schnitzler1

  • 1Cantonal Hospital Aarau, Tellstrasse 25, Aarau CH 5001, Switzerland.

Radiology. Artificial Intelligence
|August 27, 2025
PubMed
Abstract

No abstract available in PubMed .

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Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
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