Behavioural Cardiology: A Review on an Expanding Field of Cardiology-Holistic Approach
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Updated: Sep 10, 2025

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
Published on: November 7, 2019
Christos Fragoulis1, Maria-Kalliopi Spanorriga1, Irini Bega1
1First Department of Cardiology, National and Kapodistrian University of Athens, Hippokration Hospital, 114 Vassilissis Sofias Avenue, 11527 Athens, Greece.
Insights
Behavioral Cardiology integrates psychosocial factors into cardiovascular disease (CVD) prevention and treatment. The HEARTBEAT model offers personalized interventions for better chronic disease management.
Area of Science:
- Cardiology
- Psychology
- Public Health
Background:
- Cardiovascular disease (CVD) is Europe's leading cause of mortality, with over 45% of deaths attributed to it.
- Established risk factors for CVD include hypertension, diabetes, dyslipidemia, smoking, and obesity.
- Psychosocial factors such as depression, anxiety, financial stress, personality traits, and trauma significantly impact CVD development and progression.
Purpose of the Study:
- To review the HEARTBEAT model, a behavioral cardiology approach developed in Greece.
- To examine the model's alignment with European guidelines for CVD prevention and rehabilitation.
- To highlight the integration of psychosocial profiling into personalized cardiovascular care.
Main Methods:
- The HEARTBEAT model integrates psychosocial profiling with traditional risk assessment.
- It utilizes tailored evaluation tools, caregiver input, and multidisciplinary collaboration.
- The model addresses personality traits, emotional states, socioeconomic circumstances, and cultural contexts.
Main Results:
- The HEARTBEAT model serves dual purposes: primary prevention for at-risk individuals and secondary prevention for established CVD patients.
- Key implementation aspects include digital health integration, cost-effectiveness analysis, and healthcare system adaptability.
- The review identifies research gaps in psychosocial interventions and advocates for culturally sensitive adaptations, especially in resource-limited settings.
Conclusions:
- Behavioral Cardiology offers a transformative, systems-based approach bridging psychology, lifestyle medicine, and cardiovascular treatment.
- Personalized interventions addressing both biological and psychosocial determinants are crucial for optimizing chronic disease management.
- Tailored care strategies are essential for specific populations, such as older adults.
Abstract:
Cardiovascular disease (CVD) remains Europe's leading cause of mortality, responsible for >45% of deaths. Beyond established risk factors (hypertension, diabetes, dyslipidaemia, smoking, obesity), psychosocial elements-depression, anxiety, financial stress, personality traits, and trauma-significantly influence CVD development and progression. Behavioural Cardiology addresses this connection by systematically incorporating psychosocial factors into prevention and rehabilitation protocols. This review examines the HEARTBEAT model, developed by Greece's first Behavioural Cardiology Unit, which aligns with current European guidelines. The model serves dual purposes: primary prevention (targeting at-risk individuals) and secondary prevention (treating established CVD patients). It is a personalised medicine approach that integrates psychosocial profiling with traditional risk assessment, utilising tailored evaluation tools, caregiver input, and multidisciplinary collaboration to address personality traits, emotional states, socioeconomic circumstances, and cultural contexts. The model emphasises three critical implementation aspects: (1) digital health integration, (2) cost-effectiveness analysis, and (3) healthcare system adaptability. Compared to international approaches, it highlights research gaps in psychosocial interventions and advocates for culturally sensitive adaptations, particularly in resource-limited settings. Special consideration is given to older populations requiring tailored care strategies. Ultimately, Behavioural Cardiology represents a transformative systems-based approach bridging psychology, lifestyle medicine, and cardiovascular treatment. This integration may prove pivotal for optimising chronic disease management through personalised interventions that address both biological and psychosocial determinants of cardiovascular health.
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