Related Experiment Video
Updated: Sep 10, 2025

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Is meningococcal B vaccination needed in the post-COVID-19 world?
Amanda Izeli Portilho1, Elizabeth De Gaspari1
1Centro de Imunologia do Instituto Adolfo Lutz, São Paulo, SP, Brasil; Programa de Pós-Graduação Interunidades em Biotecnologia, Universidade de São Paulo, São Paulo, SP, Brasil.
Meningococcal disease caused by Neisseria meningitidis remains a global health threat, particularly serogroup B, due to vaccination gaps. Respiratory viruses may increase susceptibility to bacterial infections like meningitis.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Neisseria meningitidis is a primary cause of bacterial meningitis globally, spread via respiratory droplets.
- Meningitis poses significant public health challenges due to high rates of illness, death, and epidemic potential.
- Serogroup B meningococcal infections present ongoing challenges, with limited vaccine inclusion in national programs.
Purpose of the Study:
- To present epidemiological data on meningococcal disease.
- To discuss factors contributing to the complexity of preventing bacterial and viral infections.
Main Methods:
- Review of epidemiological data on meningococcal disease.
- Discussion of existing studies on pathogen interactions and prevention.
Main Results:
- Sustained Neisseria meningitidis serogroup B infections observed during the COVID-19 pandemic.
- Increased meningococcal disease incidence noted post-pandemic control.
- Evidence suggests respiratory viruses can enhance susceptibility to bacterial respiratory infections.
Conclusions:
- Serogroup B meningococcal disease remains a critical public health concern requiring improved prevention strategies.
- The interplay between viral and bacterial respiratory infections complicates prevention efforts.
- Further research is needed to understand and address the intricate factors influencing the prevention of both bacterial and viral infections.
More Related Videos
Related Concept Videos
Vaccinations
Microorganisms in Medicine and Therapeutics
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
Transmission-based Precautions I: Contact, Enteric, and Droplets
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

