Interrupted Inferior Caval Vein in the Era of High Prenatal Detection Highlighting Postnatal Computed Tomographic...

We reviewed those diagnosed pre- and postnatally with interrupted inferior caval vein (IICV), emphasizing the computed tomographic (CT) findings in those without complex cardiac malformations. We identified cases of IIVC diagnosed between January 2013 and December 2024. We defined non-complex cardiac malformations as secundum atrial communications with or without catheter intervention or surgery, mild semilunar valve stenosis, or a patent ductus arteriosus with or without catheter intervention or surgery. We identified 51 cases of IIVC, of which 49 had prenatal care. Of the 49 with prenatal care, 46 (94%) were diagnosed prenatally. Of the 46 prenatally diagnosed, 5 underwent fetal demise, 1 elective termination, and 40 were live born. Of the 45 live born (5 non-prenatally and 40 prenatally diagnosed), 31 (69%) had no complex cardiac malformation. Of these 31, 10 (32%) underwent CT scanning. In our experience, we noted a high prenatal detection rate for IICV, with most having no complex cardiac malformations. Further, CT scanning in a subset of patients without complex cardiac malformations demonstrated elements of left-isomeric situs, including left-atrial appendage isomerism.