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Antimicrobial Potential of Bee-Derived Products: Insights into Honey, Propolis and Bee Venom
Agnieszka Grinn-Gofroń1,2, Maciej Kołodziejczak1, Rafał Hrynkiewicz1,2
1Institute of Biology, University of Szczecin, 71-412 Szczecin, Poland.
Abstract:
Bee products, in particular honey, propolis and bee venom, are of growing scientific interest due to their broad spectrum of antimicrobial activity. In the face of increasing antibiotic resistance and the limitations of conventional therapies, natural bee-derived substances offer a promising alternative or support for the treatment of infections. This paper summarizes the current state of knowledge on the chemical composition, biological properties and antimicrobial activity of key bee products. The main mechanisms of action of honey, propolis and bee venom are presented, and their potential applications in the prevention and treatment of bacterial, viral and fungal infections are discussed. Data on their synergy with conventional drugs and prospects for use in medicine and pharmacology are also included. The available findings suggest that, with appropriate standardization and further preclinical and clinical analyses, bee products could become an effective support for the treatment of infections, especially those caused by pathogens resistant to standard therapies.
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