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Association Between Diabetes and Peri-Implantitis: Evidence From a Swedish Register-Based Study.

Anna Trullenque-Eriksson1, Fernando Valentim Bitencourt2,3, Cristiano Tomasi1

  • 1Department of Periodontology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Journal of Clinical Periodontology
|August 28, 2025
PubMed
Summary
This summary is machine-generated.

Individuals with type 1 and type 2 diabetes have an increased risk for peri-implantitis. This study found a higher prevalence in type 1 diabetes and increased incidence in type 2 diabetes.

Keywords:
dental implantsdiabetes mellitusperi‐Implantitisrisk assessment

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Area of Science:

  • Dental Implantology
  • Endocrinology
  • Public Health Research

Background:

  • Peri-implantitis, a significant complication of dental implants, affects a notable percentage of patients.
  • Diabetes mellitus, encompassing type 1 (T1D) and type 2 (T2D), is a prevalent chronic condition with systemic implications.
  • Understanding the interplay between diabetes and peri-implantitis is crucial for patient management and treatment outcomes.

Purpose of the Study:

  • To investigate the association between type 1 and type 2 diabetes and the risk of developing peri-implantitis.
  • To compare peri-implantitis prevalence and incidence in diabetic patients versus non-diabetic individuals.

Main Methods:

  • A register-based cohort study utilizing Swedish nationwide health registers from 2010 to 2020.
  • Four groups were identified: individuals with T1D, T2D, and matched non-diabetic controls.
  • Peri-implantitis was defined by registered treatment; prevalence analyzed using logistic regression, and incidence using survival analyses with propensity score matching.

Main Results:

  • Peri-implantitis prevalence was higher in T1D (21.1%) compared to non-T1D (15.2%), with an odds ratio of 1.46.
  • Prevalence was similar between T2D (20.5%) and non-T2D (18.2%), odds ratio 1.06.
  • Hazard ratios for incident peri-implantitis were 1.52 for T1D and 1.36 for T2D.

Conclusions:

  • Both type 1 and type 2 diabetes are associated with an elevated risk of peri-implantitis.
  • The increased risk for peri-implantitis in T1D was more pronounced in prevalence data.
  • For T2D, the association with peri-implantitis was primarily observed in incidence data.