Related Experiment Video
Updated: Sep 9, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
Published on: August 1, 2025
Cannabis Use in Adolescents.
Lily Rabinow1, Emily Dries1, Neal D Hoffman1
1Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, New York.
Cannabis use among youth has decreased, but increased adult use and potent products necessitate pediatrician awareness. Understanding cannabis health effects, syndromes, and treatments is crucial for youth prevention and intervention.
Area of Science:
- Pediatrics
- Public Health
- Pharmacology
Background:
- Cannabis, derived from the cannabis plant, contains psychoactive tetrahydrocannabinol (THC) and is available in various formulations.
- While recreational cannabis is legal in many US states, youth cannabis use has declined.
- Increased adult use and higher THC concentrations in products warrant greater pediatrician knowledge regarding pediatric cannabis exposure.
Purpose of the Study:
- To enhance pediatrician knowledge of cannabis and its health effects on children and adolescents.
- To describe clinical syndromes, screening tools, and treatment modalities for pediatric cannabis exposure.
- To highlight the role of pediatricians in preventive counseling and reducing youth cannabis use.
Main Methods:
- Review of longitudinal epidemiological studies on youth cannabis use.
- Analysis of clinical syndromes associated with cannabis exposure in pediatric populations.
- Description of evidence-based screening tools and treatment options for cannabis use in youth.
Main Results:
- Longitudinal studies show less than 20% of youth currently use cannabis, with decreased lifetime use over decades.
- Increasing availability of high-THC cannabis products and rising adult use present potential risks to children and adolescents.
- Pediatricians require updated knowledge on acute and chronic health effects, clinical presentations, and management strategies.
Conclusions:
- Despite declining youth use rates, the evolving cannabis landscape necessitates enhanced pediatrician preparedness.
- Pediatricians are vital in identifying and managing cannabis-related health issues in children and adolescents.
- Effective preventive counseling and intervention strategies by pediatricians can mitigate the impact of cannabis on youth health.
Related Concept Videos
CNS Stimulants: Cocaine, Amphetamines and Cannabinoids
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Cognitive Development During Adolescence
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Hallucinogens and Psychedelics
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...

