Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stress and Mental Health01:30

Stress and Mental Health

211
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
211
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

54
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
54
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

905
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
905
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

77
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
77
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

207
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
207
Bipolar Disorder01:30

Bipolar Disorder

142
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
142

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Term Effectiveness and Persistence Factors of Anti-CGRP Monoclonal Antibodies in Migraine: 2-Year Results From the EUREkA Cohort.

Neurology·2026
Same author

Clinical Manifestations of Primary CNS T-Cell Lymphoma: A Retrospective Study of Histopathologic, Molecular, and Neuroimaging Features.

Neurology·2026
Same author

Long-Term Effectiveness and Persistence Factors of Anti-CGRP Monoclonal Antibodies in Migraine: 2-Year Results From the EUREkA Cohort.

Neurology·2026
Same author

Motor adaptation does not differ when a perturbation is introduced abruptly or gradually.

Experimental brain research·2023

Related Experiment Video

Updated: Sep 9, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.3K

[Multiple comorbidities with migraine-Is there a common cause?]

Andreas Straube1

  • 1Klinik für Neurologie, Oberbayerisches Kopfschmerzzentrum, Klinikum Großhadern, Ludwig-Maximilians-Universität, 81377, München, Deutschland. andreas.straube@med.uni-muenchen.de.

Schmerz (Berlin, Germany)
|August 28, 2025
PubMed
Summary

Migraine, a common neurological disorder, is linked to increased risks of serious comorbid conditions like stroke and heart attack. Research explores shared genetic and inflammatory factors underlying these associations.

Keywords:
Anxiety disordersCardiovascular diseasesChronic painDepressionInflammation

More Related Videos

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

960
Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.0K

Related Experiment Videos

Last Updated: Sep 9, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

18.3K
Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders
05:49

Author Spotlight: Deciphering Electrical Networks Behind Complex Brain Activities and Disorders

Published on: November 1, 2024

960
Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

4.0K

Area of Science:

  • Neurology
  • Epidemiology
  • Immunology

Context:

  • Migraine is the most prevalent neurological disorder, affecting 10-14% of the population, often starting in adolescence.
  • Migraine is frequently associated with other illnesses, increasing the overall burden of the condition.
  • The risk of comorbid diseases is higher in women and those with migraine with aura.

Purpose:

  • To review epidemiological studies on diseases comorbid with migraine.
  • To explore potential neurobiological mechanisms linking migraine and comorbid conditions.
  • To discuss the role of shared genetic backgrounds and inflammatory processes.

Summary:

  • Migraine is associated with a higher risk of stroke, heart attack, hypertension, depression, anxiety, and dementia syndromes.
  • Potential links include shared genetics (e.g., CADASIL), independent chronic disease treatments, and inflammatory mechanisms.
  • Inflammation is implicated in both migraine pathogenesis and various comorbid conditions like rheumatoid arthritis, depression, and cardiovascular diseases.

Impact:

  • Current findings have not yet influenced migraine treatment.
  • Future understanding of molecular mechanisms, such as microglial activation, may lead to new therapeutic strategies.
  • This research highlights the complex interplay between migraine and other chronic diseases, emphasizing the need for integrated healthcare approaches.