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Advancing comparative placentation through spatial transcriptomics and organoid models
Francesca Soncin1,2,3
1Department of Pathology, University of California San Diego School of Medicine, La Jolla, California, United States of America.
Plos Biology
|August 29, 2025
Abstract
None:
The placenta is one of the most diverse organs among eutherian mammals, and comparative placentation studies can reveal fundamental processes that support a successful pregnancy. A new study in PLOS Biology uses swine placental organoids and in vivo spatial transcriptomics to uncover key insights into placental cell diversity and evolution.
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