New-Onset Palmar Psoriasis Following mRNA COVID-19 Vaccination: A Case Report

Palmoplantar psoriasis is a rare, chronic, localized variant of psoriasis. It represents 3-4% of all psoriasis cases and is characterized by hyperkeratotic or desquamative erythematous plaques with fissures and erosions exhibiting acral distribution. Occasionally, superimposed sterile pustulations may also occur. New-onset psoriasis and various clinical subtypes of psoriasis exacerbation have been reported following the administration of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccines, with plaque-type psoriasis being the most common. However, palmar psoriasis has not yet been reported in association with COVID-19 vaccination. Herein, we present a case of new-onset palmar psoriasis along with nail changes following mRNA COVID-19 vaccination, which was further exacerbated following successive vaccine doses.