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Fatal Complications During Photodynamic Bone Stabilization: A Case Report.
George Mina1, Taizoon Q Dhoon2, Ramin Rahimian3
1Anesthesiology and Perioperative Medicine, University of California Los Angeles, Los Angeles, USA.
Cureus
|August 29, 2025
Summary
Photodynamic bone stabilization (PBSS) is a minimally invasive procedure for bone metastases. A fatal case of cardiopulmonary collapse after balloon insufflation highlights risks in high-risk patients.
Area of Science:
- Orthopedic Surgery
- Oncology
- Cardiopulmonary Medicine
Background:
- Photodynamic bone stabilization (PBSS) offers a minimally invasive option for patients with metastatic bone disease unsuitable for traditional surgery.
- PBSS is generally successful, but potential complications require careful consideration.
Observation:
- A patient with advanced malignancy and pre-existing cardiopulmonary conditions experienced fatal cardiopulmonary collapse during PBSS.
- The event occurred during the balloon insufflation phase of the procedure.
Findings:
- The patient developed pulseless electrical activity and severe hypoxemia, leading to death.
- Embolic debris from medullary reaming is the suspected cause of the cardiopulmonary collapse.
Implications:
- This case underscores the critical need for thorough perioperative risk assessment in patients undergoing PBSS.
- Vigilant intraoperative monitoring and awareness of potential fatal embolic complications are essential for high-risk individuals.
Keywords:
balloon insufflationcardiac arrestcardiopulmonary collapsedebris embolismextra-corporeal membrane oxygenationfat embolismphotodynamic bone stabilizationphotodynamic implantpulmonary embolismvenous-arterial extra-corporeal membrane oxygenationMore Related Videos
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