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Key Factors for Neuronavigation Use in Skull Lesion Surgery
Hongbin Guo1, Dajiang Xie2, Shuxu Yang2
1Department of Neurosurgery, Qian Tang Campus of Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
World Neurosurgery
|August 29, 2025
Summary
Key factors for using neuro-navigation in skull lesion surgery include proximity to blood vessels, lesion size, palpability, skull layer, bone location, and gender. These findings aid in developing standardized guidelines for neuro-navigation application.
Area of Science:
- Neurosurgery
- Surgical Technology
- Medical Imaging
Background:
- Neuro-navigation systems enhance surgical precision.
- Standardized application frameworks are needed for neuro-navigation in skull lesion surgery.
Purpose of the Study:
- To identify key factors determining neuro-navigation use in skull lesion surgery.
- To establish a standardized framework for clinical application of neuro-navigation.
Main Methods:
- Retrospective analysis of 238 skull lesion cases (2017-2023).
- Collected clinical and surgical data, including lesion characteristics.
- Utilized correlation coefficients and Lasso regression with cross-validation for variable selection.
Main Results:
- Factors influencing neuro-navigation use identified: proximity to major vessels, maximum diameter, palpability, skull layer, bone location, and gender.
- Excluded factors: cranioplasty, general anesthesia, maximum diameter, and meningeal invasion.
- Optimal regularization parameter (λ) determined as 0.029.
Conclusions:
- Established factors provide a basis for standardized neuro-navigation guidelines in skull lesion surgery.
- Informed decision-making for neuro-navigation use in complex skull base pathologies.
