Related Experiment Video

Updated: Sep 9, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

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How interactions between oxidized DNA and the NLRP3 inflammasome fuel inflammatory disease

Angela Lackner1, Lemuel Leonidas1, Alijah Macapagal1

  • 1Laboratory of Macromolecular Structure, Department of Molecular Biology and Biochemistry, Charlie Dunlop School of Biological Sciences, University of California, Irvine, Steinhaus Hall, Irvine, CA 92694-3900, USA.

Trends in Biochemical Sciences
|August 29, 2025
PubMed

Keywords:
DNA damageinflammasomeinflammationinnate immunitymitochondrial dysregulation

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