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[Parathyrotoxic encephalopathy without hypercalcemia].

P Trouillas, F Brudon, M Saubier

    Revue Neurologique
    |January 1, 1985
    PubMed
    Summary
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    Two patients experienced dementia-like symptoms due to hyperparathyroidism. Treatment for parathyroid adenomas led to complete cognitive recovery, suggesting parathormone

    Area of Science:

    • Endocrinology
    • Neurology

    Context:

    • Hyperparathyroidism can present with neurological symptoms.
    • Dementia-like presentations are rare but possible manifestations.

    Purpose:

    • To report two cases of parathyrotoxic encephalopathy.
    • To discuss the potential role of parathormone in cognitive dysfunction.

    Summary:

    • Two patients with severe confusional episodes and EEG changes showed elevated parathormone levels.
    • Parathyroid adenomas were identified and surgically removed.
    • Complete cognitive recovery was observed post-surgery.

    Impact:

    • Highlights a treatable cause of dementia-like symptoms.
    • Suggests a direct link between parathormone and encephalopathy.

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  • Emphasizes the importance of biochemical screening in neurological cases.