Related Experiment Video For crateriform architecture
Updated: Sep 9, 2025
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Rapidly Enlarging Forearm Nodule Representing Keratoacanthoma-Type Crateriform Squamous Cell Carcinoma in a
Ahmad Y Karim1, Krithika Giresh2, Michael Vanderloo3
1Trauma Surgery, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
Abstract:
Keratoacanthoma-type crateriform squamous cell carcinoma is an uncommon cutaneous neoplasm that clinically mimics benign keratoacanthoma yet carries malignant potential. This case report describes a 54-year-old Caucasian man with occupational sun exposure and no past medical or significant family history, who developed a rapidly enlarging, dome-shaped nodule with a central keratin plug on his left forearm over six weeks. The lesion was removed via full-thickness fusiform excision with 4 mm margins and closed primarily; histopathology confirmed a crateriform squamous cell carcinoma with clear margins. The surgical site healed uneventfully, and the patient remains disease-free at the three-month follow-up. This report highlights the key clinical and histopathological features that distinguish this variant, reviews optimal surgical management and the need for ongoing surveillance, and aims to enrich the limited literature on keratoacanthoma-type crateriform squamous cell carcinoma to aid clinicians in prompt recognition and treatment.
Related Concept Videos
01:30Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
01:11Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
02:23Abnormal Proliferation