Analysis of Risk Factors for Coronary Heart Disease in Middle-Aged Men Using the Framingham Risk Score: Based on the...

The Framingham risk score (FRS) is used to assess an individual's risk of developing coronary heart disease (CHD) within 10 years by evaluating CHD risk factors. Despite the increasing mortality rate from CHD, there are limited studies examining the association between the atherogenic coefficient (AC), atherogenic index of plasma (AIP), dietary intake (assessed using a food frequency questionnaire), and FRS-CHD in Korea. The FRS is based on the following coronary risk factors: age, sex, total cholesterol, high-density lipoprotein cholesterol, smoking habits, and systolic blood pressure. The present study aimed to examine the factors that increase the risk of developing CHD in middle-aged men using the FRS based on the 2014－2015 Korea National Health and Nutrition Examination Survey (KNHANES). Data from 1,478 middle-aged men who participated in the 2014－2015 KNHANES were used. As the AC [odds ratio (OR), 6.06; 95% confidence interval (CI), 4.38－8.38; P<0.001] and AIP (OR, 3.93; 95% CI, 1.93－8.01; P<0.001) increased by 1 unit, the risk of developing CHD was significantly higher in the high-risk group than in the low-risk group after adjusting for potential confounding factors. In the high-risk group, the CHD risk decreased with an increase in egg intake per serving (OR, 0.84; 95% CI, 0.75－0.94; P<0.01). The AC, AIP, and egg intake were potent determinants of the high-risk group compared with the low-risk group. Blood cholesterol levels and diet control can decrease the CHD risk in the next 10 years.