[Isolation of fibrin assembly inhibitor from plasma and tissue extracts]

Procedures for isolation of an inhibitor of the fibrin self association are described. The procedures involved dialysis across cuprophane or cellophane T-100, ion exchange chromatography (the first method) or gel filtration (the second method). The product containing amino acid impurities was obtained after dialysis across cuprophane and ion exchange chromatography; a homogeneous inhibitor was isolated by means of dialysis across cellophane T-100 and gel filtration through Sephadex G-50.